Fig. 1
From: Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking
EndoA2 is mainly expressed in NF200-positive (NF200+) medium-to-large diameter sensory neurons. a Colocalization of EndoA2 with NF200 in DRG sections. Scale bar = 200 μm. b Size frequency distribution of EndoA2-positive (EndoA2+), NF200+ and total neurons in the DRG sections. A total of 1968 neurons from 4 mice were analyzed. c The percentage of EndoA2+ DRG neurons expressing IB4, CGRP and NF200. n = 4 mice per group. d The percentage of IB4+, CGRP+, and NF200+ DRG neurons expressing EndoA2. n = 4 mice per group. Double immunostaining of EndoA2 with NF200 in the sciatic nerve (e) and lumbar spinal dorsal cord (f) of mice. Scale bar = 100 μm (e) and 200 μm (f). EndoA2 endophilin A2, NF200 neurofilament-200, DRG dorsal root ganglion, IB4 isolectin B4, CGRP calcitonin gene-related peptide