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Fig. 8 | Military Medical Research

Fig. 8

From: Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy

Fig. 8

In situ host T-cell programming via PEGDA–PLL implants leads to Th1 and Th17-based responses. Quantification of Th1 cytokines (a) and Th17 cytokines (b) levels in serum analyzed using multiplexing. *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA with Tukey’s test. OVA ovalbumin, PEGDA–PLL polyethylene glycol diacrylate poly-L-lysine, BLV bolus lentiviruses, SLV scaffold loaded lentiviruses, IL-2 interleukin-2, IFN-γ interferon-γ, TNF-ɑ tumor necrosis factor-ɑ, IL-17A interleukin-17A, IL-21 interleukin-21, IL-22 interleukin 22

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