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Table 7 Summary of clinical trials of EVs in wound repair

From: Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges

Identifier

Condition or disease

Intervention/treatment

Phase

NCT02565264

Intractable cutaneous wound ulcer

Plasma-derived EVs

Early phase 1

NCT05078385

Second degree burn wounds

BMSC-derived EVs

Phase 1

NCT04134676

Chronic ulcer wounds

Stem cell-conditioned medium

Phase 1

NCT02138331

Diabetes mellitus type 1

MSC-derived EVs

Phase 2

Phase 3

NCT05243368

Cutaneous ulcers in diabetics

MSC-derived EVs

Not applicable

NCT04652531

Ulcer venous

Autologous EVs from serum

Not applicable

NCT05813379

Skin rejuvenation (Anti-aging)

MSC-derived EVs

Phase 1

Phase 2

NCT05243368

Diabetic foot

MSC-derived EVs

Not applicable

NCT05475418

Wounds and injuries

Adipose tissue derived exosomes

Not applicable

  1. EVs extracellular vesicles, BMSC bone marrow mesenchymal stem cell