From: Spatial transcriptomics: recent developments and insights in respiratory research
Strategy | Species | Application | Ref. |
---|---|---|---|
RNA-ISH and GeoMx DSP | Human | Spatiotemporal heterogeneity of SARS-CoV-2 infection | [113] |
RNAscope and GeoMx DSP | Human | Revealed distinct ACE2 expression loci | [116] |
GeoMx DSP | Human | Mechanism of ARDS by SARS-CoV-2 | [115] |
RNAscope and GeoMx DSP | Human | Generate COVID-19 related lung spatial atlas | [69] |
GeoMx DSP | Human | Identification of COVID-19 therapeutic target | [117] |
RNAscope and GeoMx DSP | Human | Investigation of the pathogenesis of SARS-COV-2 | [118] |
GeoMx DSP | Human | SARS-COV-2 infection up-regulates inflammatory response in COPD patients | [119] |
RNA-ISH and GeoMx DSP | Mouse | Mechanism of PASC | [114] |
RNAscope | Human | Revealed the responses to SARS-CoV-2-induced exudative DAD | [120] |
Visium | Mouse | A dynamic change in the location of T helper cells as well as their corresponding chemokines | [121] |
RNAscope and GeoMx DSP | Human | Construction of immune-mediated histopathology model of COVID-19 | [122] |
Visium | Human | The interaction between chemokines and receptors in the pathogenesis of COVID-19 lung niche | [123] |
Visium, RNAscope and GeoMx DSP | Human | Map Immune Responses to SARS-CoV-2 | [124] |