Fig. 4
From: Activatable fluorescent probes for imaging and diagnosis of rheumatoid arthritis
Structure and application of nanofluorescent probes for detecting HClO. a Schematic of dye-sensitized UCNP nanocomposites for the UCNP ratiometric probing of HClO and UV-vis absorption. Reproduced with permission from ref. [75]. Copyright (2019) Royal Society of Chemistry. b Structure and response mechanism of the probe SeTT toward HClO. c NIR-II ratiometric fluorescence imaging of osteoarthritis in rabbits using the nanoprobe. Reproduced with permission from ref. [77]. Copyright (2020) American Chemical Society. d Structure of the probes of DPPTz, DPPQu, and DPPWu. e Formation process of nanoprobes. f Imaging of HClO in λ-carrageenan-induced arthritic mice. d, e and f were reproduced with permission from ref. [81]. Copyright (2022) American Chemical Society. HClO hypochlorous acid, NIR near-infrared, UCNP upconversion nanoparticles, UV-vis ultraviolet-visible, PA photoacoustic, ClO− hypochlorite ion, NIR-II second near-infrared region, FL fluorescence imaging, UCL luminescence emission signal