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Table 4 Comparison of AI and clinical assessment methods in the prediction field of PCa

From: What benefit can be obtained from magnetic resonance imaging diagnosis with artificial intelligence in prostate cancer compared with clinical assessments?

Comparison

AI methods

Clinical assessment methods

HC model

DL model

Overall performance

Relatively high

Relatively poor

SROC-AUC*

0.86

0.75

Pooled sensitivity*

0.75

0.68

Pooled specificity*

0.84

0.79

Qualitative or quantitative

Quantitative

Quantitative/qualitative

Expert dependence

Moderate

Low

High

Consistency

High

Moderate

Manual delineation

Yes

No

No

Features

High-throughput features extracted using specific algorithms (e.g., shape, histogram and textural features)

Automatic extraction of deep and subtle image features using networks with substantial parameters

Clinical characteristics (e.g., PSA, Gleason grade and positive biopsy cores) or features for visual assessments (e.g., location, shape, size, and intensity)

  1. AI artificial intelligence, AP adverse pathology, DL deep learning, HC hand-crafted, PCa prostate cancer, PSA prostate specific antigen, SROC-AUC area under the summary receiver operator characteristic curves
  2. *Performance indexes pooled across the studies of AP prediction