Comparison | AI methods | Clinical assessment methods | |
---|---|---|---|
HC model | DL model | ||
Overall performance | Relatively high | Relatively poor | |
SROC-AUC* | 0.86 | 0.75 | |
Pooled sensitivity* | 0.75 | 0.68 | |
Pooled specificity* | 0.84 | 0.79 | |
Qualitative or quantitative | Quantitative | Quantitative/qualitative | |
Expert dependence | Moderate | Low | High |
Consistency | High | Moderate | |
Manual delineation | Yes | No | No |
Features | High-throughput features extracted using specific algorithms (e.g., shape, histogram and textural features) | Automatic extraction of deep and subtle image features using networks with substantial parameters | Clinical characteristics (e.g., PSA, Gleason grade and positive biopsy cores) or features for visual assessments (e.g., location, shape, size, and intensity) |