Image modality | Number of patients | Cancer | Target | Number of radiomics features | Commercial or open-source software | Method | References |
---|---|---|---|---|---|---|---|
CT | 878 | Lung cancer and HNSCC | Patient survival | Unspecified | Matlab, R | ML: LR, Consensus clustering, Hierarchical clustering SM: Jaccard index, Pearson correlation analysis | [15] |
CT | 188 | HNSCC | The death prognosis | 107 | PyRadiomics, 3D Slicer, Matlab | ML: LOOCV SM: Chi-square test DL: Deep learning artificial neural networks | [28] |
FDG-PET | 174 | OPC | The risk of ACM | 2–3 | Matlab, Stata/MP | ML: LOOCV, Cox proportional-hazards regression, Fine and Gray’s proportional sub-hazards model, LR, fivefold CV SM: Kaplan–Meier analysis, log-rank test, Spearman correlation analysis | [29] |
PET, CT, PET/CT | 311 | Oropharyngeal squamous cell carcinoma | PFS, OS | Unspecified | 3D Slicer, PyRadiomics, R, ggplot2 | ML: Random survival forest, Threefold stratified CV SM: t-test, Kaplan–Meier analysis, log-rank test, C-index | [30] |
CT | 44 | Laryngeal and hypo-pharyngeal cancers | DFS | 26 | Perfusion-4, ROCKIT | ML: Two-loop leave-one-out, Linear discriminant analysis SM: t-test, ICC, Kappa analysis | [31] |
MRI | 136 | EBV-related NPC | OS | 2 | Matlab, 3D Slicer, PyRadiomics | ML: Cox regression model, tenfold CV SM: Kaplan–Meier analysis, log-rank test, Mann–Whitney test or Spearman correlation analysis, ICC | [32] |
MRI | 504 | NPC | Long-term survival | 17 | AccuContour, PyRadiomics, X-tile, R | ML: LASSO, Cox regression model, tenfold CV SM: Mann–Whitney U test or t-test, Kaplan–Meier analyses, log-rank test, Hosmer–Lemeshow test, C-index | [33] |
MRI | 236 | Tongue cancer | DFS, OS | 15/17/18/25/10 | ITK-SNAP, AIMT, Python, R, SPSS | ML: PCA, SVM, Cox regression analysis, fivefold CV SM: DeLong test, Spearman correlation analysis, Kaplan–Meier analysis, log-rank test, ICC | [34] |
MRI | 346 | Rectal cancer | 3-year recurrence-free survival | 4/5/10 | GE Healthcare, 3D Slicer, R, SPSS | ML: LASSO, LR, Cox analysis SM: ICC, Wilcoxon test, Hosmer–Lemeshow test, t-test, Nonparametric test, Chi-square test and Fisher’s exact test, DeLong test | [35] |